EETs reduces LPS-induced hyperpermeability by targeting GRP78 mediated Src activation and subsequent Rho/ROCK signaling pathway

Integrity of endothelial barrier is a determinant of the prognosis in the acute lung injury caused by sepsis. The epoxyeicosatrienoic acids (EETs), metabolites of arachidonic acid, exhibit protective effects in various pathogenic states, however, whether EETs play a role in endothelial barrier enhan...

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Detalles Bibliográficos
Autores principales: Dong, Ruolan, Hu, Danli, Yang, Yan, Chen, Zhihui, Fu, Menglu, Wang, Dao Wen, Xu, Xizhen, Tu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584221/
https://www.ncbi.nlm.nih.gov/pubmed/28881620
http://dx.doi.org/10.18632/oncotarget.17331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584221/
https://www.ncbi.nlm.nih.gov/pubmed/28881620
http://dx.doi.org/10.18632/oncotarget.17331

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