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Heterogeneous nuclear ribonucleoprotein (hnRNP) L promotes DNA damage-induced cell apoptosis by enhancing the translation of p53

The tumor suppressor p53 is an essential gene in the induction of cell cycle arrest, DNA repair, and apoptosis. p53 protein is induced under cellular stress, blocking cell cycle progression and inducing DNA repair. Under DNA damage conditions, it has been reported that post-transcriptional regulatio...

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Detalles Bibliográficos
Autores principales: Seo, Ji-Young, Kim, Do-Yeon, Kim, Seong-Hoon, Kim, Hyo-Jin, Ryu, Hye Guk, Lee, Juhyun, Lee, Kyung-Ha, Kim, Kyong-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584235/
https://www.ncbi.nlm.nih.gov/pubmed/28881634
http://dx.doi.org/10.18632/oncotarget.17003