Modeling African American prostate adenocarcinoma by inducing defined genetic alterations in organoids

Genomic studies are rapidly identifying genetic alterations in human cancer, but functional validation of such alterations has been slow. Here, using human prostate cancer as a model, we have assessed the feasibility of engineering defined genetic alterations in well-known cancer driver genes to tra...

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Detalles Bibliográficos
Autores principales: Unno, Kenji, Roh, Meejeon, Yoo, Young A., Al-Shraideh, Yousef, Wang, Lu, Nonn, Larisa, Abdulkadir, Sarki A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584247/
https://www.ncbi.nlm.nih.gov/pubmed/28881646
http://dx.doi.org/10.18632/oncotarget.17230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584247/
https://www.ncbi.nlm.nih.gov/pubmed/28881646
http://dx.doi.org/10.18632/oncotarget.17230

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