DNA hypomethylation of CBS promoter induced by folate deficiency is a potential noninvasive circulating biomarker for colorectal adenocarcinomas

Aberrant DNA methylation patterns, which induced by folate deficiency, play important roles in tumorigenesis of colorectal cancer (CRC). Some DNA methylation alterations can also be detected in cell-free DNA (cfDNA) of patients’ plasma, making cfDNA an ideal noninvasive circulating biomarker. Howeve...

Descripción completa

Detalles Bibliográficos
Autores principales: Xue, Geng, Lu, Chao-Jing, Pan, Shu-Jun, Zhang, Yin-Ling, Miao, Hui, Shan, Shi, Zhu, Xiao-Ting, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584256/
https://www.ncbi.nlm.nih.gov/pubmed/28881655
http://dx.doi.org/10.18632/oncotarget.17988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584256/
https://www.ncbi.nlm.nih.gov/pubmed/28881655
http://dx.doi.org/10.18632/oncotarget.17988

Ejemplares similares