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DNA hypomethylation of CBS promoter induced by folate deficiency is a potential noninvasive circulating biomarker for colorectal adenocarcinomas
Aberrant DNA methylation patterns, which induced by folate deficiency, play important roles in tumorigenesis of colorectal cancer (CRC). Some DNA methylation alterations can also be detected in cell-free DNA (cfDNA) of patients’ plasma, making cfDNA an ideal noninvasive circulating biomarker. Howeve...
Autores principales: | Xue, Geng, Lu, Chao-Jing, Pan, Shu-Jun, Zhang, Yin-Ling, Miao, Hui, Shan, Shi, Zhu, Xiao-Ting, Zhang, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584256/ https://www.ncbi.nlm.nih.gov/pubmed/28881655 http://dx.doi.org/10.18632/oncotarget.17988 |
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