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Tumor biomarker conversion between primary and metastatic breast cancer: mRNA assessment and its concordance with immunohistochemistry

Biomarker changes between primary (PT) and metastatic tumor (MT) site may be significant in individualizing treatment strategies and can result from actual clonal evolution, biomarker conversion, or technical limitations of diagnostic tests. This study explored biomarker conversion during breast can...

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Detalles Bibliográficos
Autores principales: Stefanovic, Stefan, Wirtz, Ralph, Deutsch, Thomas M., Hartkopf, Andreas, Sinn, Peter, Varga, Zsuzsanna, Sobottka, Bettina, Sotiris, Lakis, Taran, Florin-Andrei, Domschke, Christoph, Hennigs, Andre, Brucker, Sara Y., Sohn, Christof, Schuetz, Florian, Schneeweiss, Andreas, Wallwiener, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584258/
https://www.ncbi.nlm.nih.gov/pubmed/28881657
http://dx.doi.org/10.18632/oncotarget.18006