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Bisphenol A exposure promotes HTR-8/SVneo cell migration and impairs mouse placentation involving upregulation of integrin-β1 and MMP-9 and stimulation of MAPK and PI3K signaling pathways

In this study, we investigated the effect of Bisphenol A (BPA), an endocrine-disrupting chemical, on the migration of human trophoblasts and mouse placentation by using the primary extravillous trophoblast (EVT) and its cell line HTR-8/SVneo, villous explant cultures, and pregnant mice. BPA increase...

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Detalles Bibliográficos
Autores principales: Lan, Xi, Fu, Li-Juan, Zhang, Jun, Liu, Xue-Qing, Zhang, Hui-Jie, Zhang, Xue, Ma, Ming-Fu, Chen, Xue-Mei, He, Jun-Lin, Li, Lian-Bing, Wang, Ying-Xiong, Ding, Yu-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584264/
https://www.ncbi.nlm.nih.gov/pubmed/28881663
http://dx.doi.org/10.18632/oncotarget.17882