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Malignant pericytes expressing GT198 give rise to tumor cells through angiogenesis

Angiogenesis promotes tumor development. Understanding the crucial factors regulating tumor angiogenesis may reveal new therapeutic targets. Human GT198 (PSMC3IP or Hop2) is an oncoprotein encoded by a DNA repair gene that is overexpressed in tumor stromal vasculature to stimulate the expression of...

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Detalles Bibliográficos
Autores principales: Zhang, Liyong, Wang, Yan, Rashid, Mohammad H., Liu, Min, Angara, Kartik, Mivechi, Nahid F., Maihle, Nita J., Arbab, Ali S., Ko, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584272/
https://www.ncbi.nlm.nih.gov/pubmed/28881671
http://dx.doi.org/10.18632/oncotarget.18196