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Autophagy is required for crizotinib-induced apoptosis in MET-amplified gastric cancer cells
MET amplification has been clinically credentialed as a therapeutic target in gastric cancer, but the molecular mechanisms underlying sensitivity and resistance to MET inhibitors are still not well understood. Using whole-genome mRNA expression profiling, we identified autophagy as a top molecular p...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584279/ https://www.ncbi.nlm.nih.gov/pubmed/28881678 http://dx.doi.org/10.18632/oncotarget.18386 |