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Autophagy is required for crizotinib-induced apoptosis in MET-amplified gastric cancer cells

MET amplification has been clinically credentialed as a therapeutic target in gastric cancer, but the molecular mechanisms underlying sensitivity and resistance to MET inhibitors are still not well understood. Using whole-genome mRNA expression profiling, we identified autophagy as a top molecular p...

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Detalles Bibliográficos
Autores principales:	Schroeder, Rebecca D., Choi, Woonyoung, Hong, David S., McConkey, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584279/ https://www.ncbi.nlm.nih.gov/pubmed/28881678 http://dx.doi.org/10.18632/oncotarget.18386

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