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Insulin-like growth factor-1 is a negative modulator of glucagon secretion

Glucagon secretion involves a combination of paracrine, autocrine, hormonal, and autonomic neural mechanisms. Type 2 diabetes often presents impaired glucagon suppression by insulin and glucose. Insulin-like growth factor-I (IGF-1) has elevated homology with insulin, and regulates pancreatic β-cells...

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Detalles Bibliográficos
Autores principales: Mancuso, Elettra, Mannino, Gaia C., Fatta, Concetta Di, Fuoco, Anastasia, Spiga, Rosangela, Andreozzi, Francesco, Sesti, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584282/
https://www.ncbi.nlm.nih.gov/pubmed/28881681
http://dx.doi.org/10.18632/oncotarget.18514