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Anticancer activity of calyx of Diospyros kaki Thunb. through downregulation of cyclin D1 via inducing proteasomal degradation and transcriptional inhibition in human colorectal cancer cells

BACKGROUND: Although it has been reported to contain high polyphenols, the pharmacological studies of the calyx of Diospyros kaki Thunb (DKC) have not been elucidated in detail. In this study, we elucidated anti-cancer activity and potential molecular mechanism of DKC against human colorectal cancer...

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Detalles Bibliográficos
Autores principales: Park, Su Bin, Park, Gwang Hun, Song, Hun Min, Son, Ho-Jun, Um, Yurry, Kim, Hyun-Seok, Jeong, Jin Boo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584323/
https://www.ncbi.nlm.nih.gov/pubmed/28870200
http://dx.doi.org/10.1186/s12906-017-1954-2