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3,6-Dihydroxyflavone regulates microRNA-34a through DNA methylation

BACKGROUND: Breast cancer is the common cancer in China. In previous study, we determined that 3,6-dihydroxyflavone (3,6-DHF) increases miR-34a significantly in breast carcinogenesis, but the mechanism remains unclear. METHODS: We used qRT-PCR to analyze miR-34a and ten-eleven translocation (TET)1,...

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Detalles Bibliográficos
Autores principales: Peng, Xiaoli, Chang, Hui, Chen, Junli, Zhang, Qianyong, Yu, Xiaoping, Mi, Mantian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584326/
https://www.ncbi.nlm.nih.gov/pubmed/28870206
http://dx.doi.org/10.1186/s12885-017-3638-1