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RNA-sequence data normalization through in silico prediction of reference genes: the bacterial response to DNA damage as case study

BACKGROUND: Measuring how gene expression changes in the course of an experiment assesses how an organism responds on a molecular level. Sequencing of RNA molecules, and their subsequent quantification, aims to assess global gene expression changes on the RNA level (transcriptome). While advances in...

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Detalles Bibliográficos
Autores principales: Berghoff, Bork A., Karlsson, Torgny, Källman, Thomas, Wagner, E. Gerhart H., Grabherr, Manfred G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584328/
https://www.ncbi.nlm.nih.gov/pubmed/28878825
http://dx.doi.org/10.1186/s13040-017-0150-8