Ribonucleic acid interference knockdown of IL-6 enhances the efficacy of cisplatin in laryngeal cancer stem cells by down-regulating the IL-6/STAT3/HIF1 pathway

BACKGROUND: Cisplatin has been used in the treatment of many cancers, including laryngeal cancer; however, its efficacy can be reduced due to the development of drug resistance. This study aimed to investigate whether interleukin-6 (IL-6) knockdown may enhance the efficacy of cisplatin in laryngeal...

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Detalles Bibliográficos
Autores principales: Fu, Qiang, Liu, Pengruofeng, Sun, Xiumei, Huang, Shanshan, Han, Fengchan, Zhang, Lili, Xu, Yannan, Liu, Tingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584337/
https://www.ncbi.nlm.nih.gov/pubmed/28878571
http://dx.doi.org/10.1186/s12935-017-0448-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584337/
https://www.ncbi.nlm.nih.gov/pubmed/28878571
http://dx.doi.org/10.1186/s12935-017-0448-0

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