Genetic origin of α(0)-thalassemia (SEA deletion) in Southeast Asian populations and application to accurate prenatal diagnosis of Hb Bart’s hydrops fetalis syndrome

α(0)-thalassemia of SEA deletion (—(SEA)) is common among Southeast Asian and Chinese. Using haplotype and phylogenetic analyses, we examined the origin of this defect in Southeast Asian populations. Study was done on both normal and α(0)-thalassemia alleles in 3 ethnic groups including 96 Thai, 52...

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Detalles Bibliográficos
Autores principales: Jomoui, Wittaya, Fucharoen, Goonnapa, Sanchaisuriya, Kanokwan, Charoenwijitkul, Patnaree, Maneesarn, Jitpanu, Xu, Xiangmin, Fucharoen, Supan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584512/
https://www.ncbi.nlm.nih.gov/pubmed/28381876
http://dx.doi.org/10.1038/jhg.2017.41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584512/
https://www.ncbi.nlm.nih.gov/pubmed/28381876
http://dx.doi.org/10.1038/jhg.2017.41

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