Neuron-derived CCL2 contributes to microglia activation and neurological decline in hepatic encephalopathy

BACKGROUND: CCL2 was up-regulated in neurons and involved in microglia activation and neurological decline in mice suffering from hepatic encephalopathy (HE). However, no data exist concerning the effect of neuron-derived CCL2 on microglia activation in vitro. METHODS: The rats were pretreated with...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Tan, Jinyun, Jiang, Xiaoping, Qian, Weiwei, Yang, Ting, Sun, Xijun, Chen, Zhaohui, Zhu, Qiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584513/
https://www.ncbi.nlm.nih.gov/pubmed/28870240
http://dx.doi.org/10.1186/s40659-017-0130-y

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