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Neuron-derived CCL2 contributes to microglia activation and neurological decline in hepatic encephalopathy
BACKGROUND: CCL2 was up-regulated in neurons and involved in microglia activation and neurological decline in mice suffering from hepatic encephalopathy (HE). However, no data exist concerning the effect of neuron-derived CCL2 on microglia activation in vitro. METHODS: The rats were pretreated with...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584513/ https://www.ncbi.nlm.nih.gov/pubmed/28870240 http://dx.doi.org/10.1186/s40659-017-0130-y |