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Acidic pH is essential for maintaining mast cell secretory granule homeostasis

It has been recognized for a long time that the secretory granules of mast cells are acidic, but the functional importance of maintaining an acidic pH in the mast cell granules is not fully understood. Here we addressed this issue by examining the effects of raising the pH of the mast cell secretory...

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Detalles Bibliográficos
Autores principales: Pejler, Gunnar, Hu Frisk, Jun Mei, Sjöström, Daniel, Paivandy, Aida, Öhrvik, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584528/
https://www.ncbi.nlm.nih.gov/pubmed/28492555
http://dx.doi.org/10.1038/cddis.2017.206