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Acidic pH is essential for maintaining mast cell secretory granule homeostasis
It has been recognized for a long time that the secretory granules of mast cells are acidic, but the functional importance of maintaining an acidic pH in the mast cell granules is not fully understood. Here we addressed this issue by examining the effects of raising the pH of the mast cell secretory...
Autores principales: | Pejler, Gunnar, Hu Frisk, Jun Mei, Sjöström, Daniel, Paivandy, Aida, Öhrvik, Helena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584528/ https://www.ncbi.nlm.nih.gov/pubmed/28492555 http://dx.doi.org/10.1038/cddis.2017.206 |
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