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Trial of Amiloride in Type 2 Diabetes With Proteinuria

INTRODUCTION: Renal sodium (Na(+)) retention and extracellular fluid volume expansion are hallmarks of nephrotic syndrome, which occurs even in the absence of activation of hormones that stimulate renal Na(+) transporters. Plasmin-dependent activation of the epithelial Na(+) channel has been propose...

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Detalles Bibliográficos
Autores principales: Unruh, Mark L., Pankratz, V. Shane, Demko, John E., Ray, Evan C., Hughey, Rebecca P., Kleyman, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584552/
https://www.ncbi.nlm.nih.gov/pubmed/28890943
http://dx.doi.org/10.1016/j.ekir.2017.05.008