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Isodeoxyelephantopin induces protective autophagy in lung cancer cells via Nrf2-p62-keap1 feedback loop

Isodeoxyelephantopin (ESI), isolated from Elephantopus scaber L. has been reported to exert anticancer effects. In this study, we aimed to investigate whether and how cancer cells exert protective responses against ESI treatment. Confocal fluorescence microscopy showed that ESI significantly induced...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Zhang, Jing, Huang, Zhi-Hao, Huang, Xiao-Hui, Zheng, Wei-Bin, Yin, Xing-Feng, Li, Yao-Lan, Li, Bin, He, Qing-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584574/
https://www.ncbi.nlm.nih.gov/pubmed/28617433
http://dx.doi.org/10.1038/cddis.2017.265