Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration

Tamoxifen (TAM) has recently been shown to cause acute gastric atrophy and metaplasia in mice. We have previously demonstrated that the outcome of Helicobacter felis infection, which induces similar gastric lesions in mice, is altered by deletion of specific NF-κB subunits. Nfkb1(−/−) mice developed...

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Detalles Bibliográficos
Autores principales: Burkitt, Michael D, Williams, Jonathan M, Townsend, Tristan, Hough, Rachael, Pritchard, DMark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584614/
https://www.ncbi.nlm.nih.gov/pubmed/28726772
http://dx.doi.org/10.1038/cddis.2017.332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584614/
https://www.ncbi.nlm.nih.gov/pubmed/28726772
http://dx.doi.org/10.1038/cddis.2017.332

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