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Repression of the F-box protein Skp2 is essential for actin damage-induced tetraploid G1 arrest
We previously reported that p53 plays a role as a key regulator in the tetraploid G1 checkpoint, which is activated by actin damage-induced cytokinesis blockade and then prevents uncoupled DNA replication and nuclear division without cytokinesis. In this study, we investigated a role of Skp2, which...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Society for Biochemistry and Molecular Biology
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584746/ https://www.ncbi.nlm.nih.gov/pubmed/28648144 http://dx.doi.org/10.5483/BMBRep.2017.50.7.063 |