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Chronic obstructive pulmonary disease candidate gene prioritization based on metabolic networks and functional information

Chronic obstructive pulmonary disease (COPD) is a multi-factor disease, in which metabolic disturbances played important roles. In this paper, functional information was integrated into a COPD-related metabolic network to assess similarity between genes. Then a gene prioritization method was applied...

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Detalles Bibliográficos
Autores principales: Wang, Xinyan, Li, Wan, Zhang, Yihua, Feng, Yuyan, Zhao, Xilei, He, Yuehan, Zhang, Jun, Chen, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584748/
https://www.ncbi.nlm.nih.gov/pubmed/28873096
http://dx.doi.org/10.1371/journal.pone.0184299