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Identifying genetic variants that affect viability in large cohorts
A number of open questions in human evolutionary genetics would become tractable if we were able to directly measure evolutionary fitness. As a step towards this goal, we developed a method to examine whether individual genetic variants, or sets of genetic variants, currently influence viability. Th...
Autores principales: | Mostafavi, Hakhamanesh, Berisa, Tomaz, Day, Felix R., Perry, John R. B., Przeworski, Molly, Pickrell, Joseph K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584811/ https://www.ncbi.nlm.nih.gov/pubmed/28873088 http://dx.doi.org/10.1371/journal.pbio.2002458 |
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