EpCAM aptamer-functionalized polydopamine-coated mesoporous silica nanoparticles loaded with DM1 for targeted therapy in colorectal cancer

DM1, a maytansine derivative, is a highly potential cytotoxic agent but with severe side effects; therefore, its application in clinical cancer therapy is limited. Here, in order to mitigate this intrinsic drawback of DM1, we developed mesoporous silica nanoparticles (MSNs) loaded with DM1 and surfa...

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Detalles Bibliográficos
Autores principales: Li, Yang, Duo, Yanhong, Bao, Shiyun, He, Lisheng, Ling, Kai, Luo, Jinfeng, Zhang, Yue, Huang, Hao, Zhang, Han, Yu, Xiaofang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584901/
https://www.ncbi.nlm.nih.gov/pubmed/28894364
http://dx.doi.org/10.2147/IJN.S143293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584901/
https://www.ncbi.nlm.nih.gov/pubmed/28894364
http://dx.doi.org/10.2147/IJN.S143293

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