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A fully humanized IgG-like bispecific antibody for effective dual targeting of CXCR3 and CCR6

Chemokines and their receptors are pivotal for the trafficking of leukocytes during immune responses, and host defense. However, immune cell migration also contributes to a wide variety of autoimmune and chronic inflammatory diseases. Compelling evidence suggests that both CXCR3 and CCR6 chemokine r...

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Detalles Bibliográficos
Autores principales: Robert, Remy, Juglair, Laurent, Lim, Ee X., Ang, Caroline, Wang, Carl J. H., Ebert, Gregor, Dolezal, Olan, Mackay, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584921/
https://www.ncbi.nlm.nih.gov/pubmed/28873441
http://dx.doi.org/10.1371/journal.pone.0184278