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A fully humanized IgG-like bispecific antibody for effective dual targeting of CXCR3 and CCR6
Chemokines and their receptors are pivotal for the trafficking of leukocytes during immune responses, and host defense. However, immune cell migration also contributes to a wide variety of autoimmune and chronic inflammatory diseases. Compelling evidence suggests that both CXCR3 and CCR6 chemokine r...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584921/ https://www.ncbi.nlm.nih.gov/pubmed/28873441 http://dx.doi.org/10.1371/journal.pone.0184278 |