Interleukin-17 induces human alveolar epithelial to mesenchymal cell transition via the TGF-β1 mediated Smad2/3 and ERK1/2 activation

Idiopathic pulmonary fibrosis (IPF) is a chronic and usually progressive lung disease and the epithelial-mesenchymal transition (EMT) may play an important role in the pathogenesis of pulmonary fibrosis. IL-17 is a proinflammatory cytokine which promotes EMT profiles in lung inflammatory diseases. I...

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Detalles Bibliográficos
Autores principales: Wang, Ting, Liu, Yuan, Zou, Jing-Feng, Cheng, Zhen-Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584923/
https://www.ncbi.nlm.nih.gov/pubmed/28873461
http://dx.doi.org/10.1371/journal.pone.0183972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584923/
https://www.ncbi.nlm.nih.gov/pubmed/28873461
http://dx.doi.org/10.1371/journal.pone.0183972

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