CD18 deficiency improves liver injury in the MCD model of steatohepatitis

Neutrophils and macrophages are important constituents of the hepatic inflammatory infiltrate in non-alcoholic steatohepatitis. These innate immune cells express CD18, an adhesion molecule that facilitates leukocyte activation. In the context of fatty liver, activation of infiltrated leukocytes is b...

Descripción completa

Detalles Bibliográficos
Autores principales: Pierce, Andrew A., Duwaerts, Caroline C., Siao, Kevin, Mattis, Aras N., Goodsell, Amanda, Baron, Jody L., Maher, Jacquelyn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584926/
https://www.ncbi.nlm.nih.gov/pubmed/28873429
http://dx.doi.org/10.1371/journal.pone.0183912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584926/
https://www.ncbi.nlm.nih.gov/pubmed/28873429
http://dx.doi.org/10.1371/journal.pone.0183912

Ejemplares similares