TGF-β signaling is an effective target to impair survival and induce apoptosis of human cholangiocarcinoma cells: A study on human primary cell cultures

Cholangiocarcinoma (CCA) and its subtypes (mucin- and mixed-CCA) arise from the neoplastic transformation of cholangiocytes, the epithelial cells lining the biliary tree. CCA has a high mortality rate owing to its aggressiveness, late diagnosis and high resistance to radiotherapy and chemotherapeuti...

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Detalles Bibliográficos
Autores principales: Lustri, Anna Maria, Di Matteo, Sabina, Fraveto, Alice, Costantini, Daniele, Cantafora, Alfredo, Napoletano, Chiara, Bragazzi, Maria Consiglia, Giuliante, Felice, De Rose, Agostino M., Berloco, Pasquale B., Grazi, Gian Luca, Carpino, Guido, Alvaro, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584931/
https://www.ncbi.nlm.nih.gov/pubmed/28873435
http://dx.doi.org/10.1371/journal.pone.0183932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584931/
https://www.ncbi.nlm.nih.gov/pubmed/28873435
http://dx.doi.org/10.1371/journal.pone.0183932

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