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TGF-β signaling is an effective target to impair survival and induce apoptosis of human cholangiocarcinoma cells: A study on human primary cell cultures
Cholangiocarcinoma (CCA) and its subtypes (mucin- and mixed-CCA) arise from the neoplastic transformation of cholangiocytes, the epithelial cells lining the biliary tree. CCA has a high mortality rate owing to its aggressiveness, late diagnosis and high resistance to radiotherapy and chemotherapeuti...
Autores principales: | Lustri, Anna Maria, Di Matteo, Sabina, Fraveto, Alice, Costantini, Daniele, Cantafora, Alfredo, Napoletano, Chiara, Bragazzi, Maria Consiglia, Giuliante, Felice, De Rose, Agostino M., Berloco, Pasquale B., Grazi, Gian Luca, Carpino, Guido, Alvaro, Domenico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584931/ https://www.ncbi.nlm.nih.gov/pubmed/28873435 http://dx.doi.org/10.1371/journal.pone.0183932 |
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