Cargando…

Anti-fibrotic effects of valproic acid in experimental peritoneal fibrosis

BACKGROUND: Progressive fibrous thickening of the peritoneal membrane is a complication of long-term peritoneal dialysis (PD). TGF-β/Smad pathway activation, inflammation, and neoangiogenesis play important roles in peritoneal membrane (PM) changes induced by PD. Recently, histone deacetilase inhibi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Costalonga, Elerson C., de Freitas, Luiza J., Aragone, Deise da S. P., Silva, Filipe M. O., Noronha, Irene L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584960/ https://www.ncbi.nlm.nih.gov/pubmed/28873458 http://dx.doi.org/10.1371/journal.pone.0184302

Ejemplares similares

Valproic Acid Prevents Renal Dysfunction and Inflammation in the Ischemia-Reperfusion Injury Model
por: Costalonga, Elerson C., et al.
Publicado: (2016)

Adipose-Derived Mesenchymal Stem Cells Modulate Fibrosis and Inflammation in the Peritoneal Fibrosis Model Developed in Uremic Rats
por: Costalonga, Elerson C., et al.
Publicado: (2020)

Use of paclitaxel carried in solid lipid nanoparticles to prevent peritoneal fibrosis in rats
por: Silva, Filipe M. O., et al.
Publicado: (2022)

Tamoxifen and bone morphogenic protein-7 modulate fibrosis and inflammation in the peritoneal fibrosis model developed in uremic rats
por: Silva, Filipe M. O., et al.
Publicado: (2019)

Anti-fibrotic effect of decorin in peritoneal dialysis and PD-associated peritonitis
por: Jiang, Na, et al.
Publicado: (2020)

Valproic acid and bladder healing: an experimental study in rats
por: BIONDO-SIMÕES, MARIA DE LOURDES PESSOLE, et al.
Publicado: (2022)

Improved anti-fibrotic effects by combined treatments of simvastatin and NS-398 in experimental liver fibrosis models
por: Kang, Seong Hee, et al.
Publicado: (2022)

Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis
por: Seet, Li-Fong, et al.
Publicado: (2015)

Fibrotic microtissue array to predict anti-fibrosis drug efficacy
por: Asmani, Mohammadnabi, et al.
Publicado: (2018)

Endostatin in fibrosis and as a potential candidate of anti-fibrotic therapy
por: Zhang, Zequn, et al.
Publicado: (2021)

The effects of valproic acid on skin healing: experimental study in rats
por: Biondo-Simões, Rachel, et al.
Publicado: (2022)

Valproic acid-induced hyperammonemic encephalopathy: a clinical case
por: Felizardo, M., et al.
Publicado: (2022)

T Cells in Fibrosis and Fibrotic Diseases
por: Zhang, Mengjuan, et al.
Publicado: (2020)

Disease progression in idiopathic pulmonary fibrosis under anti-fibrotic treatment
por: Cilli, Aykut, et al.
Publicado: (2023)

Angioedema induced by valproic acid
por: Yildiz, Sevler, et al.
Publicado: (2021)

Age-Dependent Anti-migraine Effects of Valproic Acid and Topiramate in Rats
por: Huang, Pokai, et al.
Publicado: (2018)

Anti-fibrotic efficacy of nintedanib in pulmonary fibrosis via the inhibition of fibrocyte activity
por: Sato, Seidai, et al.
Publicado: (2017)

Implementation of pre-clinical methodologies to study fibrosis and test anti-fibrotic therapy
por: Oakley, Fiona, et al.
Publicado: (2019)

Cost-effectiveness of the anti-fibrotics for the treatment of idiopathic pulmonary fibrosis in the United States
por: Dempsey, Timothy M., et al.
Publicado: (2022)

Anti-fibrotic therapy and lung transplant outcomes in patients with idiopathic pulmonary fibrosis
por: Astor, Todd L., et al.
Publicado: (2023)

Uridine supplementation exerts anti-inflammatory and anti-fibrotic effects in an animal model of pulmonary fibrosis
por: Cicko, Sanja, et al.
Publicado: (2015)

Population Pharmacokinetics of Valproic Acid in Pediatric and Adult Caucasian Patients
por: Teixeira-da-Silva, Paulo, et al.
Publicado: (2022)

The anti-fibrotic drug pirfenidone inhibits liver fibrosis by targeting the small oxidoreductase glutaredoxin-1
por: Xi, Yue, et al.
Publicado: (2021)

Histone deacetylase inhibition in the treatment of acute myeloid leukemia: the effects of valproic acid on leukemic cells, and the clinical and experimental evidence for combining valproic acid with other antileukemic agents
por: Fredly, Hanne, et al.
Publicado: (2013)

High Salt Promotes Inflammatory and Fibrotic Response in Peritoneal Cells
por: Pap, Domonkos, et al.
Publicado: (2023)

Replacement of Valproic Acid with New Anti-Seizure Medications in Idiopathic Generalized Epilepsy
por: Fujimoto, Ayataka, et al.
Publicado: (2022)

The Anti-Epileptic Drugs Lamotrigine and Valproic Acid Reduce the Cardiac Sodium Current
por: Jia, Lixia, et al.
Publicado: (2023)

Valproic acid-induced abnormal behavior
por: Nagalakshmi, Nanjangud Chandrashekar, et al.
Publicado: (2010)

Assessing hepatotoxicity of valproic acid in Dictyostelium
Publicado: (2012)

Hyperammonemia Associated with Valproic Acid Concentrations
por: Vázquez, Marta, et al.
Publicado: (2014)

Valproic acid-induced acute pancreatitis
por: Jain, Ayush, et al.
Publicado: (2019)

On the Digital Psychopharmacology of Valproic Acid in Mice
por: Bass, John Samuel, et al.
Publicado: (2020)

Severe Pancytopenia Induced by Valproic Acid
por: Wahba, Andrew, et al.
Publicado: (2020)

Acute pancreatitis induced by valproic acid
por: Khouadja, S., et al.
Publicado: (2021)

The Anti-Fibrotic Effect of Bone Morphogenic Protein-7(BMP-7) on Liver Fibrosis
por: Zhong, Lan, et al.
Publicado: (2013)

The Anti-fibrotic Effects and Mechanisms of MicroRNA-486-5p in Pulmonary Fibrosis
por: Ji, Xiaoming, et al.
Publicado: (2015)

Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule
por: Vijayaraj, Preethi, et al.
Publicado: (2019)

The Interaction Between Pulmonary Fibrosis and COVID-19 and the Application of Related Anti-Fibrotic Drugs
por: Shen, Hao, et al.
Publicado: (2022)

Anti-fibrotic Treatment for Pulmonary Fibrosis Induced by COVID-19: A Case Presentation
por: Sakızcı Uyar, Bahar, et al.
Publicado: (2022)

Prognosis of idiopathic pulmonary fibrosis without anti-fibrotic therapy: a systematic review
por: Khor, Yet H., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_g0f7gc679iam0mapg1r5su9g0a