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Bromide supplementation exacerbated the renal dysfunction, injury and fibrosis in a mouse model of Alport syndrome

A seminal study recently demonstrated that bromide (Br(-)) has a critical function in the assembly of type IV collagen in basement membrane (BM), and suggested that Br(-) supplementation has therapeutic potential for BM diseases. Because salts of bromide (KBr and NaBr) have been used as antiepilepti...

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Detalles Bibliográficos
Autores principales: Yokota, Tsubasa, Omachi, Kohei, Suico, Mary Ann, Kojima, Haruka, Kamura, Misato, Teramoto, Keisuke, Kaseda, Shota, Kuwazuru, Jun, Shuto, Tsuyoshi, Kai, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584969/
https://www.ncbi.nlm.nih.gov/pubmed/28873450
http://dx.doi.org/10.1371/journal.pone.0183959