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A trypanosomal orthologue of an intermembrane space chaperone has a non-canonical function in biogenesis of the single mitochondrial inner membrane protein translocase

Mitochondrial protein import is essential for Trypanosoma brucei across its life cycle and mediated by membrane-embedded heterooligomeric protein complexes, which mainly consist of trypanosomatid-specific subunits. However, trypanosomes contain orthologues of small Tim chaperones that escort hydroph...

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Detalles Bibliográficos
Autores principales: Wenger, Christoph, Oeljeklaus, Silke, Warscheid, Bettina, Schneider, André, Harsman, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584982/
https://www.ncbi.nlm.nih.gov/pubmed/28827831
http://dx.doi.org/10.1371/journal.ppat.1006550