Cargando…

Genetic epidemiology of dengue viruses in phase III trials of the CYD tetravalent dengue vaccine and implications for efficacy

This study defined the genetic epidemiology of dengue viruses (DENV) in two pivotal phase III trials of the tetravalent dengue vaccine, CYD-TDV, and thereby enabled virus genotype-specific estimates of vaccine efficacy (VE). Envelope gene sequences (n = 661) from 11 DENV genotypes in 10 endemic coun...

Descripción completa

Detalles Bibliográficos
Autores principales: Rabaa, Maia A, Girerd-Chambaz, Yves, Duong Thi Hue, Kien, Vu Tuan, Trung, Wills, Bridget, Bonaparte, Matthew, van der Vliet, Diane, Langevin, Edith, Cortes, Margarita, Zambrano, Betzana, Dunod, Corinne, Wartel-Tram, Anh, Jackson, Nicholas, Simmons, Cameron P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584992/
https://www.ncbi.nlm.nih.gov/pubmed/28871961
http://dx.doi.org/10.7554/eLife.24196