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Butyrylcholinesterase regulates central ghrelin signaling and has an impact on food intake and glucose homeostasis

BACKGROUND: Ghrelin is the only orexigenic hormone known to stimulate food intake and promote obesity and insulin resistance. We recently showed that plasma ghrelin is controlled by butyrylcholinesterase (BChE), which has a strong impact on feeding and weight gain. BChE knockout (KO) mice are prone...

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Detalles Bibliográficos
Autores principales: Chen, V P, Gao, Y, Geng, L, Brimijoin, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585042/
https://www.ncbi.nlm.nih.gov/pubmed/28529331
http://dx.doi.org/10.1038/ijo.2017.123