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Butyrylcholinesterase regulates central ghrelin signaling and has an impact on food intake and glucose homeostasis
BACKGROUND: Ghrelin is the only orexigenic hormone known to stimulate food intake and promote obesity and insulin resistance. We recently showed that plasma ghrelin is controlled by butyrylcholinesterase (BChE), which has a strong impact on feeding and weight gain. BChE knockout (KO) mice are prone...
Autores principales: | Chen, V P, Gao, Y, Geng, L, Brimijoin, S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585042/ https://www.ncbi.nlm.nih.gov/pubmed/28529331 http://dx.doi.org/10.1038/ijo.2017.123 |
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