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Jak kinase 3 signaling in microgliogenesis from the spinal nestin(+) progenitors in both development and response to injury

During spinal cord development, endogenous progenitors expressing nestin can migrate into the target and differentiate into neurons and other glial cells. Microglial cells can also be derived from nestin(+) progenitor cells, even in the adult brain. Knockdown of Jak kinase 3 (Jak3) signaling can inc...

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Detalles Bibliográficos
Autores principales: Barua, Sumit, Chung, Jee-In, Kim, A Young, Lee, Soo-Yeon, Lee, Soo Hwan, Baik, Eun Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585131/
https://www.ncbi.nlm.nih.gov/pubmed/28817455
http://dx.doi.org/10.1097/WNR.0000000000000854