Screening for Natural Inhibitors of Topoisomerases I from Rhamnus davurica by Affinity Ultrafiltration and High-Performance Liquid Chromatography–Mass Spectrometry

Topoisomerase I (Topo I) catalyzes topological interconversion of duplex DNA during DNA replication and transcription, and has been deemed as important antineoplastic targets. In this study, the fraction R.d-60 from ethyl acetate extracts of Rhamnus davurica showed higher inhibitory rates against SG...

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Detalles Bibliográficos
Autores principales: Chen, Guilin, Guo, Mingquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Plant Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585147/
https://www.ncbi.nlm.nih.gov/pubmed/28919906
http://dx.doi.org/10.3389/fpls.2017.01521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585147/
https://www.ncbi.nlm.nih.gov/pubmed/28919906
http://dx.doi.org/10.3389/fpls.2017.01521

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