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Altered Immune Activation and IL-23 Signaling in Response to Candida albicans in Autoimmune Polyendocrine Syndrome Type 1

OBJECTIVE: Autoimmune polyendocrine syndrome type 1 (APS-1) is a rare, childhood onset disease caused by mutations in the autoimmune regulator (AIRE) gene. Chronic mucocutaneous candidiasis (CMC) is one of the three major disease components and is, to date, mainly explained by the presence of neutra...

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Detalles Bibliográficos
Autores principales: Bruserud, Øyvind, Bratland, Eirik, Hellesen, Alexander, Delaleu, Nicolas, Reikvam, Håkon, Oftedal, Bergithe E., Wolff, Anette S. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585148/
https://www.ncbi.nlm.nih.gov/pubmed/28919897
http://dx.doi.org/10.3389/fimmu.2017.01074