Selection for energy efficiency drives strand-biased gene distribution in prokaryotes

Lagging-strand genes accumulate more deleterious mutations. Genes are thus preferably located on the leading strand, an observation known as strand-biased gene distribution (SGD). Despite of this mechanistic understanding, a satisfactory quantitative model is still lacking. Replication-transcription...

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Detalles Bibliográficos
Autores principales: Gao, Na, Lu, Guanting, Lercher, Martin J., Chen, Wei-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585166/
https://www.ncbi.nlm.nih.gov/pubmed/28874819
http://dx.doi.org/10.1038/s41598-017-11159-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585166/
https://www.ncbi.nlm.nih.gov/pubmed/28874819
http://dx.doi.org/10.1038/s41598-017-11159-3

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