The Dietary Constituent Falcarindiol Promotes Cholesterol Efflux from THP-1 Macrophages by Increasing ABCA1 Gene Transcription and Protein Stability

We report increased cholesterol efflux from macrophages in the presence of falcarindiol, an important dietary constituent present in commonly used vegetables and medicinal plants. Falcarindiol (3–20 μM) increased cholesterol efflux from THP-1-derived macrophages. Western blot analysis showed an incr...

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Detalles Bibliográficos
Autores principales: Wang, Limei, Palme, Veronika, Schilcher, Nicole, Ladurner, Angela, Heiss, Elke H., Stangl, Herbert, Bauer, Rudolf, Dirsch, Verena M., Atanasov, Atanas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585181/
https://www.ncbi.nlm.nih.gov/pubmed/28919859
http://dx.doi.org/10.3389/fphar.2017.00596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585181/
https://www.ncbi.nlm.nih.gov/pubmed/28919859
http://dx.doi.org/10.3389/fphar.2017.00596

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