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Serum-Mediated Oxidative Stress from Systemic Sclerosis Patients Affects Mesenchymal Stem Cell Function

OBJECTIVES: Properties of mesenchymal stromal/stem cells (MSCs) from systemic sclerosis (SSc) patients have been reported to be altered. MSC-based therapy may therefore rely on the use of allogeneic MSCs from healthy subjects. Here, we investigated whether heterologous MSCs could exhibit altered pro...

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Detalles Bibliográficos
Autores principales: Fonteneau, Guillaume, Bony, Claire, Goulabchand, Radjiv, Maria, Alexandre T. J., Le Quellec, Alain, Rivière, Sophie, Jorgensen, Christian, Guilpain, Philippe, Noël, Danièle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585199/
https://www.ncbi.nlm.nih.gov/pubmed/28919892
http://dx.doi.org/10.3389/fimmu.2017.00988