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Dioxin Receptor Adjusts Liver Regeneration After Acute Toxic Injury and Protects Against Liver Carcinogenesis

The aryl hydrocarbon receptor (AhR) has roles in cell proliferation, differentiation and organ homeostasis, including the liver. AhR depletion induces undifferentiation and pluripotency in normal and transformed cells. Here, AhR-null mice (AhR−/−) were used to explore whether AhR controls liver rege...

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Detalles Bibliográficos
Autores principales: Moreno-Marín, Nuria, Barrasa, Eva, Morales-Hernández, Antonio, Paniagua, Beroé, Blanco-Fernández, Gerardo, Merino, Jaime M., Fernández-Salguero, Pedro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585208/
https://www.ncbi.nlm.nih.gov/pubmed/28874739
http://dx.doi.org/10.1038/s41598-017-10984-w