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Current-direction/amplitude-dependent single channel gating kinetics of mouse pannexin 1 channel: a new concept for gating kinetics

The detailed single-channel gating kinetics of mouse pannexin 1 (mPanx1) remains unknown, although mPanx1 is reported to be a voltage-activated anion-selective channel. We investigated characteristics of single-channel conductances and opening and closing rates of mPanx1 using patch-clamp techniques...

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Detalles Bibliográficos
Autores principales: Nomura, Takeshi, Taruno, Akiyuki, Shiraishi, Makoto, Nakahari, Takashi, Inui, Toshio, Sokabe, Masahiro, Eaton, Douglas C., Marunaka, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585217/
https://www.ncbi.nlm.nih.gov/pubmed/28874774
http://dx.doi.org/10.1038/s41598-017-10921-x