Epiphyseal bone formation occurs via thyroid hormone regulation of chondrocyte to osteoblast transdifferentiation

Endochondral ossification in the diaphysis of long bones has been studied in-depth during fetal development but not postnatally in the epiphysis. Immunohistochemical studies revealed that Sox9 and Col2 expressing immature chondrocytes in the epiphysis transition into prehypertrophic and hypetrophic...

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Detalles Bibliográficos
Autores principales: Aghajanian, Patrick, Xing, Weirong, Cheng, Shaohong, Mohan, Subburaman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585223/
https://www.ncbi.nlm.nih.gov/pubmed/28874841
http://dx.doi.org/10.1038/s41598-017-11050-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585223/
https://www.ncbi.nlm.nih.gov/pubmed/28874841
http://dx.doi.org/10.1038/s41598-017-11050-1

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