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Epiphyseal bone formation occurs via thyroid hormone regulation of chondrocyte to osteoblast transdifferentiation
Endochondral ossification in the diaphysis of long bones has been studied in-depth during fetal development but not postnatally in the epiphysis. Immunohistochemical studies revealed that Sox9 and Col2 expressing immature chondrocytes in the epiphysis transition into prehypertrophic and hypetrophic...
Autores principales: | Aghajanian, Patrick, Xing, Weirong, Cheng, Shaohong, Mohan, Subburaman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585223/ https://www.ncbi.nlm.nih.gov/pubmed/28874841 http://dx.doi.org/10.1038/s41598-017-11050-1 |
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