Deep Phospho- and Phosphotyrosine Proteomics Identified Active Kinases and Phosphorylation Networks in Colorectal Cancer Cell Lines Resistant to Cetuximab

Abnormality in cellular phosphorylation is closely related to oncogenesis. Thus, kinase inhibitors, especially tyrosine kinase inhibitors (TKIs), have been developed as anti-cancer drugs. Genomic analyses have been used in research on TKI sensitivity, but some types of TKI resistance have been uncla...

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Detalles Bibliográficos
Autores principales: Abe, Yuichi, Nagano, Maiko, Kuga, Takahisa, Tada, Asa, Isoyama, Junko, Adachi, Jun, Tomonaga, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585238/
https://www.ncbi.nlm.nih.gov/pubmed/28874695
http://dx.doi.org/10.1038/s41598-017-10478-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585238/
https://www.ncbi.nlm.nih.gov/pubmed/28874695
http://dx.doi.org/10.1038/s41598-017-10478-9

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